Clinical Research Fellow Oncology Early Phase Clinical Trials

Job summary

This appointment is an excellent opportunity for clinicians in any speciality at any stage of their career to gain experience of clinical research in a leading research organisation, as well as those aiming for a career in Medical or Clinical Oncology, Experimental Medicine or Pharmaceutical Medicine to advance within a supportive environment.

Main duties of the job

The primary role of the post holder is to provide medical support for Early Phase Clinical Trials in Cancer, including advanced therapies such as cell and gene therapies, anti-cancer immunotherapy and intra-tumoural therapeutics. The studies will be delivered within the Oncology Department at Imperial College NHS Trust as part of the National Institute of Health Research (NIHR) Imperial BRC newly funded Oncology and Haematology Translational Research Centre and within the NIHR Imperial Clinical Research Facility. The post holder will work directly with experienced senior researchers supporting the implementation of patient-based clinical trials across the earliest phases of clinical development (phase IA, IB and II) in an established clinical academic environment that benefits from both on-site acute medical services and experienced administrative support. The postholder will also help to develop risk assessments and risk mitigation strategies for new early phase studies. The postholder will also attend regular oncology clinics at the Hammersmith Site (Phase I clinics) to facilitate recruitment to clinical studies and gain further experience in the multi-disciplinary management of cancer patients. The activity within the Unit will support training in drug development, study design, pharmacovigilance, project management, and conduct of clinical trials, as well as regulatory aspects of clinical experimentation. Access to an ePortfolio will be facilitated for post holder

About us

The Department's focus is to deliver our research and education mission in an environment where everyone can thrive: Translational technology: To innovate, develop and apply new technologies, techniques and computationally intense systems medicine approaches to enhance medical and surgical diagnostics and prognostics, surgical interventions and augment clinical decision-making to improve patient safety across all areas of medical and surgical practice. Mechanisms of disease and patient complexity: To understand and model mechanisms of disease and patient complexity in relation to personalised healthcare problems, and to elucidate the basis of population disease risks. To create and deliver top-quality education in innovative learning environments to inspire and unite the next generation of healthcare and health science leaders. Our department undertakes innovative research programmes tailored to developing world-leading academics. Such individuals will provide the healthcare solutions of the future. We are committed to supporting our staff and student community to achieve our aims in research and education, by actively developing our Athena SWAN profile through our Culture and Committee. This integrates an enormous diversity of scientific and medical research activities at the interface of the College and the associated Imperial College Healthcare Trust.

Job description

Job responsibilities

Job summary This appointment is an excellent opportunity for clinicians in any speciality at any stage of their career to gain experience of clinical research in a leading research organisation, as well as those aiming for a career in Medical or Clinical Oncology, Experimental Medicine or Pharmaceutical Medicine to advance within a supportive environment. The Clinical Research Fellow will work in the Division of Cancer based at the Hammersmith Hospital Campus with a dynamic group of clinicians and scientists engaged in evaluating novel therapeutics for cancer treatment. Duties and responsibilities The primary role of the post holder is to provide medical support for Early Phase Clinical Trials in Cancer, including advanced therapies such as cell and gene therapies, anti-cancer immunotherapy and intra-tumoural therapeutics. The studies will be delivered within the Oncology Department at Imperial College NHS Trust as part of the National Institute of Health Research (NIHR) Imperial BRC newly funded Oncology and Haematology Translational Research Centre and within the NIHR Imperial Clinical Research Facility (ICRF). The post holder will work directly with experienced senior researchers supporting the implementation of patient-based clinical trials across the earliest phases of clinical development (phase IA, IB and II) in an established clinical academic environment that benefits from both on-site acute medical services and experienced administrative support. The postholder will also help to develop risk assessments and risk mitigation strategies for new early phase studies. The postholder will also attend regular oncology clinics at the Hammersmith Site (Phase I clinics) to facilitate recruitment to clinical studies and gain further experience in the multi-disciplinary management of cancer patients. The activity within the Unit will support training in drug development, study design, pharmacovigilance, project management, and conduct of clinical trials, as well as regulatory aspects of clinical experimentation. Access to an ePortfolio will be facilitated for post holders not in higher specialist training. The ICRF hosts the Imperial College Masters course in Clinical Research, and there are a number of relevant lectures, teaching workshops and modules that the post holder may attend if time allows. Essential requirements

  • You will have a Degree in medicine or equivalent
  • You will have minimum experience equivalent to FY2 or above
  • You will be knowledgeable, curious and passionate
  • You will be able to use your initiative to pursue opportunities to broaden your skills portfolio
  • You should provide evidence of being able to work independently and as a part of a team
  • Further information Alongside clinical work within Oncology and the Clinical Research Facility, the post-holder will be required to assist and lead in the conduction of clinical research project in cancer drug development as directed by Dr David Pinato. The research project will entail project design, experimental work in addition to data analysis and reporting the results in peer-reviewed journals. This is a Full Time and fixed term role until August 2025 based at the South Kensington Campus Should you require any further details on the role please contact: Dr. David Pinato - . The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/ The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College's care are treated with full respect, and that all staff involved with this work show due consideration at every level. http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research/

    Person Specification

    Qualifications

    Essential
    • Degree in medicine or equivalent
    • Full GMC registration with licence to practice
    • Advanced Life Support training
    • Completed FY2 or equivalent with experience in general medicine or general surgery
    • Sound knowledge and experience in the management of critically ill patients E
    • A post registration or recent experience in the NHS in a medical or surgical post E
    • Clinical skills (physical examination, ECG, Chest X Ray, radiology
    • interpretation, biochemistry and haematology results interpretation, basic
    • clinical skills including
    • venepuncture, IV cannulation)
    Desirable
    • Please refer to Job description on Job criteria for further information

    Experience

    Essential
    • Advanced Life Support training
    • Completed FY2 or equivalent with experience in general medicine or general surgery
    • Sound knowledge and experience in the management of critically ill patients
    • A post registration or recent experience in the NHS in a medical or surgical post
    • Clinical skills (physical examination, ECG, Chest X Ray, radiology
    • interpretation, biochemistry and haematology results interpretation, basic
    • clinical skills including venepuncture, IV cannulation)
    Desirable
    • Please refer to Job description on Job criteria for further information

    Disclosure and Barring Service Check

    This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

    Certificate of Sponsorship

    Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website.

    From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants.

    UK Registration

    Applicants must have current UK professional registration. For further information please see NHS Careers website.

    Employer details

    Employer name

    Imperial College London

    Address

    The Commonwealth Building, The Hammersmith Hospital, Du Cane Road,

    London

    W12 0NN


    Employer's website

    https://www.imperial.ac.uk/

    Company
    Imperial College London
    Location
    London, United Kingdom W12 0NN
    Employment Type
    Fixed-Term
    Salary
    Negotiable
    Posted
    Company
    Imperial College London
    Location
    London, United Kingdom W12 0NN
    Employment Type
    Fixed-Term
    Salary
    Negotiable
    Posted